Absolute ultrasound perfusion parameter quantification of a tissue-mimicking phantom using bolus tracking [Correspondence]

Martin Mezl; Radovan Jirik; Vratislav Harabis; Radim Kolar; Michal Standara; Kim Nylund; Odd Helge Gilja; Torfinn Taxt

doi:10.1109/TUFFC.2014.006896

Absolute ultrasound perfusion parameter quantification of a tissue-mimicking phantom using bolus tracking [Correspondence]

IEEE Trans Ultrason Ferroelectr Freq Control. 2015 May;62(5):983-7. doi: 10.1109/TUFFC.2014.006896.

Authors

Martin Mezl, Radovan Jirik, Vratislav Harabis, Radim Kolar, Michal Standara, Kim Nylund, Odd Helge Gilja, Torfinn Taxt

PMID: 25965688
DOI: 10.1109/TUFFC.2014.006896

Abstract

This study presents three methods for absolute quantification in ultrasound perfusion analysis based on bolus tracking. The first two methods deconvolve the perfusion time sequence with a measured AIF, using a nonparametric or a parametric model of the tissue residue function, respectively. The third method is a simplified approach avoiding deconvolution by assuming a narrow AIF. A phantom with a dialyzer filter as a tissue-mimicking model was used for evaluation. Estimated mean transit times and blood volumes were compared with the theoretical values. A match with a maximum error of 12% was achieved.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Equipment Design
Humans
Image Processing, Computer-Assisted / methods*
Models, Cardiovascular
Perfusion Imaging / instrumentation
Perfusion Imaging / methods*
Phantoms, Imaging*
Signal Processing, Computer-Assisted
Ultrasonography / instrumentation
Ultrasonography / methods*