Toxicity and bioaccumulation of bromadiolone to earthworm Eisenia fetida

Jing Liu; Kang Xiong; Xiaoqing Ye; Jianyun Zhang; Ye Yang; Li Ji

doi:10.1016/j.chemosphere.2015.04.058

Toxicity and bioaccumulation of bromadiolone to earthworm Eisenia fetida

Chemosphere. 2015 Sep:135:250-6. doi: 10.1016/j.chemosphere.2015.04.058. Epub 2015 May 15.

Authors

Jing Liu¹, Kang Xiong², Xiaoqing Ye², Jianyun Zhang², Ye Yang², Li Ji³

Affiliations

¹ MOE Key Laboratory of Environmental Remediation and Ecosystem Health, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Institute of Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Research Center for Air Pollution and Health, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China.
² MOE Key Laboratory of Environmental Remediation and Ecosystem Health, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Institute of Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China.
³ MOE Key Laboratory of Environmental Remediation and Ecosystem Health, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China; Institute of Environmental Science, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address: jilienv@zju.edu.cn.

PMID: 25965004
DOI: 10.1016/j.chemosphere.2015.04.058

Abstract

Bromadiolone, a potent second-generation anticoagulant rodenticide, has been extensively used worldwide for the field control of rodents. Invertebrates may be at risk from primary poisoning as a result of bromadiolone bait applications. However, there are few data regarding the toxicity and bioaccumulation of bromadiolone to earthworms. In this study, we reported that bromadiolone was toxic to earthworms at 1mg/kg soil, which is a likely concentration in the field following application of bromadiolone baits. Exposure to bromadiolone resulted in a significant inhibition of earthworm growth. The antioxidant activities of superoxide dismutase and catalase were slightly increased in earthworms, while malondialdehyde content (as a molecular marker indicative of the damage to lipid peroxidation) was dominantly elevated over the duration of exposure. Bromadiolone in soil is bioaccumulative to earthworms. The biota to soil accumulation factors (BSAFs) of bromadiolone were concentration dependent and BSAFs decreased as the level of bromadiolone in soil increased. These results suggest earthworms are not only the potential subject to primary poisoning but also the source of secondary exposure for insectivores and scavengers following application of bromadiolone.

Keywords: Anticoagulant rodenticide; Bioaccumulation; Bromadiolone; Earthworm; Toxicity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

4-Hydroxycoumarins / toxicity*
Animals
Biomarkers / metabolism
Catalase / metabolism
Lipid Peroxidation
Malondialdehyde
Oligochaeta / metabolism*
Soil
Soil Pollutants / analysis
Soil Pollutants / toxicity*
Superoxide Dismutase / metabolism

Substances

4-Hydroxycoumarins
Biomarkers
Soil
Soil Pollutants
Malondialdehyde
Catalase
Superoxide Dismutase
bromadiolone