Lentigo Maligna Melanoma With Local and Distant Blue Nevus-like Metastases

Am J Dermatopathol. 2015 Oct;37(10):e126-8. doi: 10.1097/DAD.0000000000000292.

Abstract

Melanoma or melanoma metastases can rarely mimic blue nevi clinically and/or histologically, presenting a diagnostic pitfall for both the clinician and the dermatopathologist. We report a case of an invasive lentigo maligna melanoma with subsequent development of multiple, cutaneous blue nevus-like localized metastases followed by a distant metastasis, heralding widespread systemic metastases.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Hutchinson's Melanotic Freckle / chemistry
  • Hutchinson's Melanotic Freckle / secondary*
  • Hutchinson's Melanotic Freckle / surgery
  • MART-1 Antigen / analysis
  • Male
  • Nevus, Blue / secondary*
  • Predictive Value of Tests
  • Skin Neoplasms / chemistry
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Staining and Labeling
  • Time Factors
  • Treatment Outcome

Substances

  • Biomarkers, Tumor
  • MART-1 Antigen