Occurrence and genetic diversity of human cosavirus in influent and effluent of wastewater treatment plants in Arizona, United States

Arch Virol. 2015 Jul;160(7):1775-9. doi: 10.1007/s00705-015-2435-x. Epub 2015 May 5.

Abstract

Human cosavirus (HCoSV) is a novel member of the family Picornaviridae. We investigated the prevalence and genetic diversity of HCoSV in influent and effluent wastewater in Arizona over a 12-month period, from August 2011 to July 2012. HCoSV sequences were identified in six (25%) influent samples and one (4%) effluent sample, with the highest concentration of 3.24 × 10(5) and 1.54 × 10(3) copies/liter in influent and effluent, respectively. The strains were characterized based on their 5' untranslated region and classified into species A and D, demonstrating that genetically heterogeneous HCoSV were circulating with a clear temporal shift of predominant strains in the study area.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5' Untranslated Regions
  • Arizona
  • Base Sequence
  • Genetic Variation*
  • Humans
  • Molecular Sequence Data
  • Phylogeny
  • Picornaviridae / classification
  • Picornaviridae / genetics*
  • Picornaviridae / isolation & purification
  • Waste Disposal Facilities
  • Wastewater / virology*

Substances

  • 5' Untranslated Regions
  • Waste Water

Associated data

  • GENBANK/AB935714
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