The results of organ-preserving operations in 243 patients with peptic ulcer of the pyloric part of the stomach and duodenum are analysed; 88% of patients were operated on in the occurrence of life-threatening complications of the disease. The main type of surgical operation was selective proximal vagotomy which was isolated only in 44 cases. The immediate and late sequela of the operations were evaluated by means of the aspiration-titration method of studying acid production, pH-metry, roentgenoscopy, electrogastrography, and esophagogastroscopy. The late results of the vagotomy were studied during prolonged continuous medical observation of the patients. A socioeconomic impact of SPV is shown. The results of organ-preserving operation were excellent in 84.4%, satisfactory in 10.5%, and poor in 5.1% of patients according to Visick's classification.