Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia

Ann Hematol. 2015 Aug;94(8):1431-3. doi: 10.1007/s00277-015-2391-2. Epub 2015 May 3.

Authors

Shinichi Ogawa¹, Yasuhisa Yokoyama, Kazumi Suzukawa, Toru Nanmoku, Naoki Kurita, Masanori Seki, Koichiro Maie, Takuya Suyama, Naoko Takaiwa, Mamiko Sakata-Yanagimoto, Naoshi Obara, Yuichi Hasegawa, Shigeru Chiba

Affiliation

¹ Department of Hematology, University of Tsukuba Hospital, 1-1-1, Tennodai, Tsukuba, Ibaraki, Japan.

PMID: 25933678
DOI: 10.1007/s00277-015-2391-2

No abstract available

Publication types

Case Reports
Letter

MeSH terms

ETS Translocation Variant 6 Protein
Hippo Signaling Pathway
Humans
Leukemia, Myeloid, Acute / diagnosis*
Leukemia, Myeloid, Acute / genetics*
Male
Middle Aged
Protein Serine-Threonine Kinases / genetics*
Proto-Oncogene Proteins c-ets / genetics*
Repressor Proteins / genetics*
Serine-Threonine Kinase 3
Translocation, Genetic / genetics*

Substances

Proto-Oncogene Proteins c-ets
Repressor Proteins
Protein Serine-Threonine Kinases
STK3 protein, human
Serine-Threonine Kinase 3