Encapsulation of Hemin in Metal-Organic Frameworks for Catalyzing the Chemiluminescence Reaction of the H2O2-Luminol System and Detecting Glucose in the Neutral Condition

ACS Appl Mater Interfaces. 2015 Jun 3;7(21):11322-9. doi: 10.1021/acsami.5b01706. Epub 2015 May 18.

Abstract

Novel metal-organic frameworks (MOFs) based solid catalysts have been synthesized by encapsulating Hemin into the HKUST-1 MOF materials. These have been first applied in the chemiluminescence field with outstanding performance. The functionalized MOFs not only maintain an excellent catalytic activity inheriting from Hemin but also can be cyclically utilized as solid mimic peroxidases in the neutral condition. The synthesized Hemin@HKUST-1 composites have been used to develop practical sensors for H2O2 and glucose with wide response ranges and low detection limits. It was envisioned that catalyst-functionalized MOFs for chemiluminescence sensing would have promising applications in green, selective, and sensitive detection of target analytes in the future.

Keywords: H2O2; HKUST-1; Hemin; catalysis; chemiluminescence; glucose.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glucose / analysis*
  • Glucose / chemistry
  • Glucose Oxidase / chemistry
  • Hemin / chemistry*
  • Hydrogen Peroxide / chemistry*
  • Luminescent Measurements / methods*
  • Luminol / chemistry
  • Metal-Organic Frameworks
  • Nanocapsules / chemistry*
  • Nanocapsules / ultrastructure
  • Organometallic Compounds / chemistry*
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Metal-Organic Frameworks
  • Nanocapsules
  • Organometallic Compounds
  • bis(1,3,5-benzenetricarboxylate)tricopper(II)
  • Luminol
  • Hemin
  • Hydrogen Peroxide
  • Glucose Oxidase
  • Glucose