A scanometric antibody probe for facile and sensitive immunoassays

Chem Commun (Camb). 2015 May 25;51(42):8865-7. doi: 10.1039/c5cc02838h.

Abstract

We have developed a novel scanometric antibody probe for rapid, sensitive, and naked-eye-visible immunoassays. Using this probe, we clearly demonstrated the successful scanometric detection and identification of influenza A viruses on a microarray. In addition, the sensitivity of the scanometric immunoassay was comparable to that of the fluorescence-based method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / analysis*
  • Antibodies, Viral / chemistry
  • Antibodies, Viral / immunology
  • Fluorescence
  • Gold / chemistry
  • Immunoassay / methods*
  • Molecular Probes / analysis*
  • Molecular Probes / chemistry
  • Molecular Probes / immunology
  • Orthomyxoviridae / immunology*
  • Orthomyxoviridae / isolation & purification*
  • Peptides / chemistry

Substances

  • Antibodies, Viral
  • Molecular Probes
  • Peptides
  • Gold