Abstract
The antibiotic β-indomycinone was isolated from Streptomyces sp. IFM11607 by cytotoxicity-guided fractionation against human gastric adenocarcinoma AGS cells, and the geometry of its δ17,18-double bond was revised from E to Z based on the coupling constant.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anthraquinones / chemistry*
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Anthraquinones / isolation & purification
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Anthraquinones / metabolism
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Anthraquinones / pharmacology*
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / metabolism
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Antineoplastic Agents / pharmacology*
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Cell Line, Tumor
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Cell Survival / drug effects
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Humans
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Molecular Structure
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Streptomyces / chemistry*
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Streptomyces / metabolism
Substances
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Anthraquinones
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Antineoplastic Agents