Clinical use of Bevacizumab in treating refractory glaucoma

J Med Life. 2015 Jan-Mar;8(1):8-12.

Abstract

Bevacizumab is a recombinant humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF). Though other VEGF inhibitors are being approved for the treatment of ophthalmological conditions, bevacizumab found its way into ophthalmology and clinical practice all around the world. The objective of this review is to present the ophthalmic dosage and administration pathways of bevacizumab in treating refractory glaucoma patients.

Abbreviations: VEGF = vascular endothelial growth factor, FDA = Food and Drug Administration, AMD = age-related macular degeneration.

Keywords: bevacizumab; glaucoma; trabeculectomy; vascular endothelial growth factor.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Angiogenesis Inhibitors / administration & dosage
  • Angiogenesis Inhibitors / pharmacokinetics
  • Angiogenesis Inhibitors / therapeutic use
  • Bevacizumab / administration & dosage
  • Bevacizumab / pharmacokinetics
  • Bevacizumab / therapeutic use*
  • Dose-Response Relationship, Drug
  • Glaucoma / drug therapy*
  • Humans

Substances

  • Angiogenesis Inhibitors
  • Bevacizumab