PLCG1 Gene Mutations Are Uncommon in Cutaneous T-Cell Lymphomas

Charline Caumont; Audrey Gros; Cécile Boucher; Pierre Mélard; Martina Prochazkova-Carlotti; Elodie Laharanne; Anne Pham-Ledard; Béatrice Vergier; Edith Chevret; Marie Beylot-Barry; Jean-Philippe Merlio; David Cappellen

doi:10.1038/jid.2015.161

PLCG1 Gene Mutations Are Uncommon in Cutaneous T-Cell Lymphomas

J Invest Dermatol. 2015 Sep;135(9):2334-2337. doi: 10.1038/jid.2015.161. Epub 2015 Apr 24.

Affiliations

¹ EA2406, Histology and Molecular Pathology of Tumours, University of Bordeaux, Bordeaux, France; Tumor Bank and Tumor Biology Laboratory, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France.
² Tumor Bank and Tumor Biology Laboratory, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France.
³ Department of Pathology, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France.
⁴ EA2406, Histology and Molecular Pathology of Tumours, University of Bordeaux, Bordeaux, France.
⁵ EA2406, Histology and Molecular Pathology of Tumours, University of Bordeaux, Bordeaux, France; Department of Dermatology, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France.
⁶ EA2406, Histology and Molecular Pathology of Tumours, University of Bordeaux, Bordeaux, France; Department of Pathology, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France.
⁷ EA2406, Histology and Molecular Pathology of Tumours, University of Bordeaux, Bordeaux, France; Tumor Bank and Tumor Biology Laboratory, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France. Electronic address: jp.merlio@u-bordeaux.fr.
⁸ EA2406, Histology and Molecular Pathology of Tumours, University of Bordeaux, Bordeaux, France; Tumor Bank and Tumor Biology Laboratory, Centre Hospitalier Universitaire de Bordeaux, Hôpital Haut-Lévêque, Pessac, France. Electronic address: david.cappellen@u-bordeaux.fr.

PMID: 25910029
DOI: 10.1038/jid.2015.161

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Biopsy, Needle
DNA Mutational Analysis
Humans
Lymphoma, T-Cell, Cutaneous / genetics*
Lymphoma, T-Cell, Cutaneous / pathology
Mutation*
Phospholipase C gamma / genetics*
Sampling Studies
Sensitivity and Specificity
Skin Neoplasms / genetics*
Skin Neoplasms / pathology

Substances

PLCG1 protein, human
Phospholipase C gamma