Bisphenol A contamination in soft drinks as a risk for children's health in Italy

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(7):1207-14. doi: 10.1080/19440049.2015.1031713. Epub 2015 Apr 27.

Abstract

Bisphenol A (BPA) was determined in sugary carbonated, non-carbonated and milk-based beverages, through HLPC-fluorescence detection and confirmed by LC-MS/MS, in a selection of brands that are mostly consumed by Italian children. The daily intake was determined through the WHO budget method (BM). BPA was found at detectable levels in 57% of carbonated beverages, in 50% of non-carbonated and in 100% of milk-based beverages. The median concentrations were 1.24 µg l(-1) (range = < LOD-4.98 µg l(-1)) in canned carbonated beverages and 0.18 µg l(-1) (< LOD-1.78 µg l(-1)) in non-canned carbonated beverages. In non-carbonated beverages, median concentrations were 0.80 µg l(-1) (< LOD-2.79 µg l(-1)) and 0.18 µg l(-1) (< LOD-3.58 µg l(-1)), respectively, for canned and non-canned beverages; in milk-based products the BPA median concentration was 3.60 µg l(-1) (1.00-17.65 µg l(-1)). BPA daily intake from sugary drink consumption in children ranged from 0.008 to 1.765 µg kg(-1) bw day(-1). The median exposure values for the 'best' and 'worst' cases were 0.16% and 0.47% respectively of the EFSA t-TDI for BPA (4 µg kg(-1) bw day(-1)), and 10.59% and 35.30% of the t-TDI when the maximum levels were considered.

Keywords: BPA; chemical contamination; children’s intake; sugary beverages.

MeSH terms

  • Benzhydryl Compounds / chemistry*
  • Benzhydryl Compounds / toxicity*
  • Carbonated Beverages / analysis*
  • Child
  • Food Contamination / analysis
  • Food Packaging
  • Humans
  • Italy
  • Phenols / chemistry*
  • Phenols / toxicity*
  • Risk Assessment

Substances

  • Benzhydryl Compounds
  • Phenols
  • bisphenol A