Is the third interferon a charm?

Sci Transl Med. 2015 Apr 22;7(284):284fs16. doi: 10.1126/scitranslmed.aaa2817. Epub 2015 Apr 22.

Abstract

IFNλ restores blood-brain barrier integrity after disruption by West Nile virus, reducing virus invasion of the brain and increasing survival of infected mice (Lazear et al., this issue).

Publication types

  • Comment

MeSH terms

  • Animals
  • Blood-Brain Barrier*
  • Humans
  • Interferons / pharmacology*
  • Neurons / virology*
  • Receptors, Cytokine / metabolism*
  • Receptors, Interferon / metabolism*
  • West Nile Fever / immunology*

Substances

  • Receptors, Cytokine
  • Receptors, Interferon
  • Interferons