2-Azanorbornane--a versatile chiral aza-Diels-Alder cycloadduct: preparation, applications in stereoselective synthesis and biological activity

Org Biomol Chem. 2015 Jun 14;13(22):6116-48. doi: 10.1039/c5ob00173k.

Abstract

The review presents the achievements in the field of preparation of chiral 2-azanorbornyl derivatives and their application in various stereoselective reactions as well as in biomimetic studies.

Publication types

  • Review

MeSH terms

  • Animals
  • Antidiuretic Hormone Receptor Antagonists / chemical synthesis
  • Antidiuretic Hormone Receptor Antagonists / chemistry
  • Antidiuretic Hormone Receptor Antagonists / pharmacology*
  • Antioxidants / chemical synthesis
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Azabicyclo Compounds / chemical synthesis*
  • Azabicyclo Compounds / chemistry
  • Azabicyclo Compounds / pharmacology*
  • Biomimetic Materials / chemical synthesis
  • Biomimetic Materials / chemistry
  • Biomimetic Materials / pharmacology*
  • Cyclization
  • Humans
  • Hydrogen Peroxide / antagonists & inhibitors
  • Molecular Structure
  • Receptors, Vasopressin / metabolism
  • Stereoisomerism

Substances

  • Antidiuretic Hormone Receptor Antagonists
  • Antioxidants
  • Azabicyclo Compounds
  • Receptors, Vasopressin
  • Hydrogen Peroxide