Abstract
Various 2-[5-(aryl)-1,2,4-oxadiazol-3-yl]quinazolin-4(3H)-ones have been synthesized from the reaction of diaminoglyoxime-based nitrones with methyl 2-aminobenzoate or 2-aminobenzamide in the presence of acetic acid at 100 °C. The reaction was extended as a one-pot three-component approach starting from diaminoglyoxime, aldehyde and methyl 2-aminobenzoate.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Aldehydes / chemistry
-
Aminobenzoates / chemistry
-
Chemistry Techniques, Synthetic
-
Models, Molecular
-
Molecular Conformation
-
Nitrogen Oxides / chemistry*
-
Oximes / chemistry*
-
Quinazolinones / chemical synthesis*
-
Quinazolinones / chemistry*
Substances
-
Aldehydes
-
Aminobenzoates
-
Nitrogen Oxides
-
Oximes
-
Quinazolinones
-
diaminoglyoxime
-
nitrones