Study design, rationale and methods for a population-based study of myopia in schoolchildren: the Myopia Investigation study in Taipei

Clin Exp Ophthalmol. 2015 Sep-Oct;43(7):612-20. doi: 10.1111/ceo.12532. Epub 2015 Jun 26.

Abstract

Background: To describe the study design, rationale and methodology of the Myopia Investigation Study in Taipei (MIT).

Design: The MIT was a city-wide, population-based cohort study.

Participants: Participants were grade 2 students (Fall 2013) of all 153 elementary schools in Taipei City.

Methods: The baseline data on the risk factors for myopia development was collected by parent-administered questionnaire surveys covering demographics, medical history, parental myopia, time spent on near work and outdoor activities, reading habits and eye care-seeking behaviour. Ocular examinations focused on the measurement of visual acuity (unaided and best-corrected) and refractive status (before and after cycloplegia), which will be carried out for the eligible schoolchildren biannually for 3 years consecutively. Once myopic children are identified, case manager-led telecoaching for health-care instructions and reminders will be delivered to parents or caregivers.

Main outcome measures: To build a comprehensive database for prevalence, incidence and risk factors of early childhood myopia over a 3-year follow-up period.

Results: Of all 19 374 eight-year-old schoolchildren (10 210 [52.7%] boys) eligible for the MIT, 16 486 (85.1%) responded to the questionnaire, 12 019 (62.0%) were examined during the third quarter of 2013 and 11 590 (59.8%) (6267 [52.9%] boys) completed cycloplegic autorefraction on both eyes and were enrolled for further data analysis. There was no significant difference in terms of demographics between the analysed participants and all grade 2 students in Taipei City.

Conclusions: Data from the MIT will provide population-based information concerning the prevalence, incidence and risk factors for myopia development among young schoolchildren in a metropolitan area of Taiwan.

Keywords: cohort study; methodology; myopia; population-based study; schoolchildren.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caregivers
  • Child
  • Epidemiologic Methods*
  • Female
  • Health Surveys
  • Humans
  • Incidence
  • Male
  • Myopia / epidemiology*
  • Parents
  • Prevalence
  • Research Design*
  • Risk Factors
  • Surveys and Questionnaires
  • Taiwan / epidemiology
  • Urban Population / statistics & numerical data