Platelet-rich plasma in the treatment of subcutaneous venous access device scars: a head-to-head patient survey

Biomed Res Int. 2015:2015:630601. doi: 10.1155/2015/630601. Epub 2015 Mar 24.

Abstract

Introduction: Platelet-rich plasma (PRP) is a product widely used in sports medicine, tissue repair, and general surgery. A recent meta-analysis showed this product to be beneficial when introduced into a wound area, be it intra-articular (i.e., joint-injections) or direct introduction onto the wound surface.

Methods: Between the years of 2012 and 2014 a questionnaire evaluating surgical outcome after port (venous access device) removal was answered by 100 patients in the control group and 20 patients in a PRP group, leading to a total of 120 patients in this single center, retrospective, subjective outcome evaluation.

Results: No statistical difference was shown in postsurgical complication rates, postsurgical pain, decreased mobility, and overall quality of life. A significant difference was shown in overall patient satisfaction and the desire to further improve port area scarring. Results differed significantly in favor of the PRP group. Interestingly, approximately 40.2% of patients are dissatisfied with the surgical outcome after port removal in the control group. This result, though surprising, may be improved to 10% dissatisfaction when a PRP product is used.

Conclusion: PRP products such as Arthrex ACP are safe to use and present an additional option in improving surgical outcome.

Publication types

  • Meta-Analysis

MeSH terms

  • Arthroscopy / adverse effects
  • Cicatrix / drug therapy*
  • Cicatrix / physiopathology
  • Humans
  • Patient Satisfaction
  • Platelet-Rich Plasma*
  • Postoperative Complications / drug therapy*
  • Postoperative Complications / pathology
  • Retrospective Studies
  • Surveys and Questionnaires
  • Treatment Outcome
  • Veins / drug effects*
  • Veins / injuries
  • Veins / surgery
  • Wound Healing / drug effects