Abstract
The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology*
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology*
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Genome, Viral / drug effects
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Gram-Negative Bacteria / drug effects
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Gram-Negative Bacteria / metabolism
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Gram-Positive Bacteria / drug effects
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Gram-Positive Bacteria / metabolism
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Metal Nanoparticles / chemistry*
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Metals, Heavy / chemistry
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Metals, Heavy / pharmacology*
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Reactive Oxygen Species / metabolism
Substances
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Anti-Bacterial Agents
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Antiviral Agents
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Metals, Heavy
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Reactive Oxygen Species