Deep brain stimulation and multiple sclerosis: Therapeutic applications

Holly A Roy; Tipu Z Aziz

doi:10.1016/j.msard.2014.02.003

Deep brain stimulation and multiple sclerosis: Therapeutic applications

Mult Scler Relat Disord. 2014 Jul;3(4):431-9. doi: 10.1016/j.msard.2014.02.003. Epub 2014 Feb 19.

Authors

Holly A Roy¹, Tipu Z Aziz²

Affiliations

¹ Nuffield Department of Surgical Science, John Radcliffe Hospital, Oxford OX3 9DU, UK.
² Nuffield Department of Surgical Science, John Radcliffe Hospital, Oxford OX3 9DU, UK. Electronic address: tipu.aziz@nds.ox.ac.uk.

PMID: 25877053
DOI: 10.1016/j.msard.2014.02.003

Abstract

Deep brain stimulation is a neurosurgical technique that can be used to alleviate symptoms in a growing number of neurological conditions through modulating activity within brain networks. Certain applications of deep brain stimulation are relevant for the management of symptoms in multiple sclerosis. In this paper we discuss existing treatment options for tremor, facial pain and urinary dysfunction in multiple sclerosis and discuss evidence to support the potential use of deep brain stimulation for these symptoms.

Keywords: Chronic pain; Deep brain stimulation (DBS); Multiple sclerosis (MS); Tremor; Trigeminal neuralgia; Urinary bladder.

Publication types

Review