Lanthanum, constipation, bafflying X-rays and a perforated colonic diverticulum

Clin Kidney J. 2012 Aug;5(4):331-3. doi: 10.1093/ckj/sfs073. Epub 2012 Jul 6.

Abstract

Lanthanum carbonate (LC) is used as a phosphate binder in dialysed patients. Abdominal pain and constipation are known side effects of its use. Furthermore, in radiological studies, LC tablets are seen as intense radio-opaque deposits within the entire gastrointestinal tract-findings which can lead to diagnostic misinterpretations. An elderly patient on peritoneal dialysis and taking LC presented with peritonitis, secondary to a perforated colonic diverticulum. The possible association between the use of LC, worsening constipation and complications arising from colonic diverticular disease, are discussed.

Keywords: constipation; dialysis; diverticular disease; lanthanum carbonate.