Turn-on and label-free fluorescence detection of lead ions based on target-induced G-quadruplex formation

Chem Commun (Camb). 2015 May 11;51(38):8165-8. doi: 10.1039/c5cc01590a. Epub 2015 Apr 15.

Abstract

Using a guanine-rich sequence (AGRO100) and N-methyl mesoporphyrin IX (NMM), a turn-on and label-free fluorescent Pb(2+) sensor with high sensitivity and low background fluorescence was presented as a representative of five turn-on sensing systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescence*
  • Fluorescent Dyes / chemistry*
  • G-Quadruplexes*
  • Guanine / chemistry*
  • Ions / analysis
  • Lead / analysis*
  • Mesoporphyrins / chemistry*
  • Spectrometry, Fluorescence

Substances

  • Fluorescent Dyes
  • Ions
  • Mesoporphyrins
  • N-methylmesoporphyrin IX
  • Lead
  • Guanine