Actinomyces meyeri brain abscess following dental extraction

BMJ Case Rep. 2015 Apr 13:2015:bcr2014207548. doi: 10.1136/bcr-2014-207548.

Abstract

We describe the rare occurrence of an Actinomyces meyeri cerebral abscess in a 55-year-old woman following a dental extraction. This patient presented with a 2-day history of hemisensory loss, hyper-reflexia and retro-orbital headache, 7 days following a dental extraction for apical peridonitis. Neuroimaging showed a large left parietal abscess with surrounding empyema. The patient underwent craniotomy and drainage of the abscess. A. meyeri was cultured. Actinomycosis is a rare cause of cerebral abscess. The A. meyeri subtype is particularly rare, accounting for less than 1% of specimens. This case describes an unusually brief course of the disease, which is usually insidious. Parietal lobe involvement is unusual as cerebral abscesses usually have a predilection for the frontal and temporal regions of the brain. Although there are no randomised trials to guide therapy, current consensus is to use a prolonged course of intravenous antibiotics, followed by 6-12 months of oral therapy.

Publication types

  • Case Reports

MeSH terms

  • Actinomyces / isolation & purification*
  • Actinomycosis / diagnostic imaging
  • Actinomycosis / drug therapy
  • Actinomycosis / etiology*
  • Actinomycosis / microbiology
  • Anti-Bacterial Agents / therapeutic use
  • Brain Abscess / diagnostic imaging
  • Brain Abscess / drug therapy
  • Brain Abscess / etiology*
  • Brain Abscess / microbiology
  • Diagnosis, Differential
  • Female
  • Gait Disorders, Neurologic / diagnosis
  • Gait Disorders, Neurologic / microbiology
  • Headache / diagnosis
  • Headache / microbiology
  • Humans
  • Middle Aged
  • Radiography
  • Tooth Extraction / adverse effects*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents