Skin disease in pregnancy

Best Pract Res Clin Obstet Gynaecol. 2015 Jul;29(5):732-40. doi: 10.1016/j.bpobgyn.2015.03.005. Epub 2015 Mar 17.

Abstract

Skin manifestations during pregnancy are common and diversified. This review will focus on the most important entities to be recognized by obstetricians. These are, on the one hand, physiological changes, where unnecessary investigations should be avoided, and on the other, the specific dermatoses of pregnancy. These develop electively in pregnancy, and they are currently grouped into three disorders: polymorphic eruption of pregnancy, atopic eczema of pregnancy, and pemphigoid gestationis. Arguments for recognition of these are presented including detection of anti-BP180 antibodies. Follow-up and treatment depend on the precise diagnosis. Risks in fetal prognosis may occur in rare pemphigoid gestationis cases.

Keywords: atopic eruption of pregnancy; impetigo herpetiformis; pemphigoid gestationis; polymorphic eruption of pregnancy; pregnancy; skin abnormality.

Publication types

  • Review

MeSH terms

  • Dermatitis, Atopic / drug therapy
  • Dermatitis, Atopic / pathology
  • Female
  • Humans
  • Hyperpigmentation / physiopathology
  • Pemphigoid Gestationis / drug therapy
  • Pemphigoid Gestationis / immunology
  • Pemphigoid Gestationis / pathology
  • Pregnancy
  • Pregnancy Complications / pathology*
  • Pregnancy Complications / physiopathology*
  • Skin Diseases / drug therapy
  • Skin Diseases / pathology*
  • Skin Diseases / physiopathology*
  • Skin Diseases, Vascular / physiopathology
  • Skin Physiological Phenomena