Iris metastasis from prostate carcinoma: a case report and review of the literature

Abstract

Despite the high incidence of prostate carcinoma, metastases of the uvea are very rare and the iris localization is even more. Only a few cases worldwide have been described so far. We report here the case of a 66-year-old man diagnosed with a metastatic prostate carcinoma. Nine months later, he developed brain and skin metastases. A couple of weeks later, the metastatic lesion appeared on his left iris. He has received whole brain radiation therapy including the iris lesion in the radiation fields. Through this case report and a literature review, we discuss the incidence, the different clinical presentations and the impact on the survival prognosis of this uncommon metastatic site.

Keywords: Cancer de prostate; Iris; Metastasis; Métastase; Prostate carcinoma; Radiation therapy; Radiothérapie; Tumeur uvéal; Uveal tumor.