Abstract
A turn-on fluorescent probe was designed for selective cyanide anion sensing in aqueous and biological environments. The probe underwent an intramolecular crossed-benzoin reaction in the presence of KCN to expel the fluorophore resorufin. This probe was sensitive to KCN concentrations as low as 4 nM in aqueous media.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anions / analysis
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Benzoin / chemistry*
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Cyanides / analysis*
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Fluorescent Dyes / chemistry*
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HeLa Cells
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Humans
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Microscopy, Confocal
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Molecular Structure
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Oxazines / chemistry
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Potassium Cyanide / analysis*
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Spectrometry, Fluorescence
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Water / chemistry
Substances
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Anions
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Cyanides
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Fluorescent Dyes
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Oxazines
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Water
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resorufin
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Benzoin
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Potassium Cyanide