Next-Generation Sequencing: Targeting Targeted Therapies

Clin Cancer Res. 2015 Aug 15;21(16):3584-5. doi: 10.1158/1078-0432.CCR-15-0407. Epub 2015 Apr 6.

Abstract

Next-generation sequencing (NGS) has given new perspective in oncology. With the ongoing development of targeted therapies, NGS is evolving molecular diagnostics by providing comprehensive interrogation of clinically actionable genomic aberrations in tumors. Having this assay as the primary testing method produces clinically beneficial results. See related article by Drilon et al., p. 3631.

Publication types

  • Comment

MeSH terms

  • Adenocarcinoma / genetics*
  • Female
  • Gene Rearrangement*
  • Genome, Human*
  • High-Throughput Nucleotide Sequencing*
  • Humans
  • Lung Neoplasms / genetics*
  • Male