Antimicrobial bacterial cellulose nanocomposites prepared by in situ polymerization of 2-aminoethyl methacrylate

Carbohydr Polym. 2015 Jun 5:123:443-53. doi: 10.1016/j.carbpol.2015.01.063. Epub 2015 Feb 7.

Abstract

Antimicrobial bacterial cellulose/poly(2-aminoethyl methacrylate) (BC/PAEM) nanocomposites were prepared by in situ radical polymerization of 2-aminoethyl methacrylate, using variable amounts of N,N-methylenebis(acrylamide) (MBA) as cross-linker. The obtained nanocomposites were characterized in terms of their structure, morphology, thermal stability, mechanical properties and antibacterial activity. The ensuing composite membranes were significantly more transparent than those of pure BC and showed improved thermal and mechanical properties. The antibacterial activity of the obtained nanocomposites was assessed towards a recombinant bioluminescent Escherichia coli and only the non-crosslinked nanocomposite (BC/PAEM) proved to have antibacterial activity.

Keywords: Antibacterial properties; Bacterial cellulose; Bioluminescent Escherichia coli; In situ radical polymerization; Nanocomposite membranes; Poly(2-aminoethyl methacrylate) (PAEM).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemical synthesis
  • Anti-Infective Agents / chemistry*
  • Anti-Infective Agents / pharmacology
  • Cellulose / chemistry*
  • Escherichia coli / drug effects
  • Luminescent Measurements
  • Magnetic Resonance Spectroscopy
  • Methacrylates / chemistry*
  • Microscopy, Electron, Scanning
  • Nanocomposites / chemistry*
  • Nanocomposites / toxicity
  • Polymerization
  • Spectroscopy, Fourier Transform Infrared
  • Tensile Strength
  • Thermogravimetry
  • X-Ray Diffraction

Substances

  • Anti-Infective Agents
  • Methacrylates
  • 2-aminoethylmethacrylate
  • Cellulose