Laboratory Studies of Aedes aegypti Attraction to Ketones, Sulfides, and Primary Chloroalkanes Tested Alone and in Combination with L-Lactic Acid

J Am Mosq Control Assoc. 2015 Mar;31(1):63-70. doi: 10.2987/14-6452R.1.

Abstract

The attraction of female Aedes aegypti to single compounds and binary compositions containing L-lactic acid and an additional saturated compound from a set of ketones, sulfides, and chloroalkanes was studied using a triple-cage dual-port olfactometer. These chemical classes were studied because of their structural relation to acetone, dimethyl disulfide, and dichloromethane, which have all been reported to synergize attraction to L-lactic acid. Human odors, carbon dioxide, and the binary mixture of L-lactic acid and CO₂served as controls for comparison of attraction responses produced by the binary mixtures. All tested mixtures that contained chloroalkanes attracted mosquitoes at synergistic levels, as did L-lactic acid and CO₂. Synergism was less frequent in mixtures of L-lactic acid with sulfides and ketones; in the case of ketones, synergistic attraction was observed only for L-lactic acid combined with acetone or butanone. Suppression or inhibition of attraction response was observed for combinations that contained ketones of C7-C12 molecular chain length (optimum in the C8-C10 range). This inhibition effect is similar to that observed previously for specific ranges of carboxylic acids, aldehydes, and alcohols.

Keywords: blends; lures; mosquito attractments; olfactometer.

MeSH terms

  • Aedes / drug effects*
  • Aedes / physiology
  • Animals
  • Chemotaxis / drug effects*
  • Female
  • Hydrocarbons, Chlorinated / pharmacology
  • Ketones / pharmacology
  • Lactic Acid / pharmacology*
  • Olfactometry
  • Pheromones / pharmacology*
  • Sulfides / pharmacology

Substances

  • Hydrocarbons, Chlorinated
  • Ketones
  • Pheromones
  • Sulfides
  • insect attractants
  • Lactic Acid