Integrated treatment for lower-limb stage II thromboangiitis obliterans by interventional therapy and oral administration of Chinese medicine: a randomized controlled clinical trial

J Tradit Chin Med. 2015 Feb;35(1):41-6. doi: 10.1016/s0254-6272(15)30007-8.

Abstract

Methods: Ninety lower-limb stage II or worse TAO patients were randomly divided into three groups: group A (30 cases) treated by intervention and oral administration of Chinese medicine; group B (30 cases) treated by intervention alone; and group C (30 cases) treated only with oral administration of Chinese medicine. Therapeutic effects were observed, including the cure rate; the recurrence rate after one month, three months, six months, nine months, and one year; the ankle brachial indexes; the incidence of complications; and the level of C-reactive protein and erythrocyte sedimentation rate.

Results: Group A had significantly better clinically curative effects, related indexes, and outcomes during the long-term follow-up survey, than that of groups B and C.

Conclusion: Integrated treatment is more effective for treating lower-limb stage II or worse TAO.

Objective: To observe if integrated treatment is better than other therapies for lower-limb stage II thromboangiitis obliterans (TAO).

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Aged
  • Aspirin / administration & dosage*
  • C-Reactive Protein / metabolism
  • Drug Therapy, Combination
  • Drugs, Chinese Herbal / administration & dosage*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Thromboangiitis Obliterans / drug therapy*
  • Thromboangiitis Obliterans / metabolism
  • Thromboangiitis Obliterans / pathology

Substances

  • Drugs, Chinese Herbal
  • C-Reactive Protein
  • Aspirin