Self-assembly in aqueous solution of amphiphilic graft copolymers from oxidized carboxymethylcellulose

Eduardo Bordallo; Jacques Rieumont; Marcio José Tiera; Manuel Gómez; Massimo Lazzari

doi:10.1016/j.carbpol.2015.01.082

Self-assembly in aqueous solution of amphiphilic graft copolymers from oxidized carboxymethylcellulose

Carbohydr Polym. 2015 Jun 25:124:43-9. doi: 10.1016/j.carbpol.2015.01.082. Epub 2015 Feb 12.

Authors

Eduardo Bordallo¹, Jacques Rieumont², Marcio José Tiera³, Manuel Gómez⁴, Massimo Lazzari⁵

Affiliations

¹ Cuban Research Institute of Sugar Cane, Havana, Cuba; Department of Chemistry and Environmental Science, Institute of Biosciences, Humanities, and Exact Science (IBILCE), San Paulo University (UNESP), San Paulo, SP, Brazil; Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, A Coruña, Spain. Electronic address: bordallolopez@gmail.com.
² Faculty of Chemistry, Havana University, Havana, Cuba.
³ Department of Chemistry and Environmental Science, Institute of Biosciences, Humanities, and Exact Science (IBILCE), San Paulo University (UNESP), San Paulo, SP, Brazil.
⁴ Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, A Coruña, Spain.
⁵ Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, A Coruña, Spain. Electronic address: massimo.lazzari@usc.es.

PMID: 25839792
DOI: 10.1016/j.carbpol.2015.01.082

Abstract

A series of oxidized carboxymethylcellulose-graft-poly(ethylene glycol)-dodecylamine (OCMC-g-PEG-DDA) was prepared by using an appositely prepared PEG with terminal amino groups and different amounts of DDA. The nanoaggregates formed in aqueous solution were characterized by surface tension measurements, fluorescence spectroscopy, dynamic light scattering (DLS) and scanning electron microscopies (SEM and TEM). The micelles showed narrow hydrodynamic size distributions and diameters varying from 163 to 193nm depending on the ratio of DDA to PEG chains. The DDA content in the graft copolymers also affected the core-shell interfacial compactness.

Keywords: Amphiphilic graft copolymer; Carboxymethylcellulose; Fluorescence; Micellization; PEGylation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amines / chemistry
Carboxymethylcellulose Sodium / analogs & derivatives*
Carboxymethylcellulose Sodium / chemistry
Micelles
Microscopy, Electron
Polyethylene Glycols / chemistry
Spectrometry, Fluorescence
Surface Tension
Surface-Active Agents / chemistry*
Water / chemistry

Substances

Amines
Micelles
Surface-Active Agents
Water
Polyethylene Glycols
Carboxymethylcellulose Sodium
dodecylamine