Multiple paraneoplastic syndromes revealing non-small cell lung carcinoma

Pan Afr Med J. 2014 Nov 3:19:237. doi: 10.11604/pamj.2014.19.237.4409. eCollection 2014.

Abstract

A broad spectrum of paraneoplastic dermatoses is associated with lung cancer. We report herein a 56-year-old man who presented an association of erythroderma, acquired ichthyosis, palmo-plantar keratoderma, hypereosinophilia and hyper IgE. In light of these clinical and biological assessments an underlying malignancy had been suspected. A thoracic, abdominal and pelvic computed tomography showed a left hilar mass. The patient underwent a left pneumonectomy and the histological study had confirmed a non-small cell lung cancer. Recognition of cutaneous paraneoplastic syndromes is important since it leads to prompt diagnosis of an underlying malignancy and consequently a better management and prognosis of the disease.

Keywords: Carcinoma; IgE; paraneoplastic dermatoses.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Paraneoplastic Syndromes / diagnosis*
  • Paraneoplastic Syndromes / pathology
  • Pneumonectomy
  • Prognosis
  • Small Cell Lung Carcinoma / diagnosis*
  • Small Cell Lung Carcinoma / pathology
  • Tomography, X-Ray Computed