Photodynamic therapy for diffuse choroidal hemangioma in a child with Sturge-Weber syndrome

J AAPOS. 2015 Apr;19(2):181-3. doi: 10.1016/j.jaapos.2014.10.032. Epub 2015 Mar 28.

Abstract

Sturge-Weber syndrome is a rare neurocutaneous disorder involving the leptomeninges, skin of the face, and, in 40% of cases, diffuse choroidal hemangioma. We report the case of a 6-year-old girl with Sturge-Weber syndrome and a large diffuse choroidal hemangioma with retinal detachment involving the majority of the retina. The patient underwent photodynamic therapy. The retinal detachment resolved completely within 3 months of treatment. This case represents the youngest patient in the literature to undergo successful treatment with photodynamic therapy for Sturge-Weber syndrome-associated diffuse choroidal hemangioma.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Choroid Neoplasms / diagnosis
  • Choroid Neoplasms / drug therapy*
  • Choroid Neoplasms / etiology
  • Female
  • Fluorescein Angiography
  • Hemangioma / diagnosis
  • Hemangioma / drug therapy*
  • Hemangioma / etiology
  • Humans
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use*
  • Porphyrins / therapeutic use*
  • Sturge-Weber Syndrome / complications*
  • Sturge-Weber Syndrome / diagnosis
  • Sturge-Weber Syndrome / physiopathology
  • Verteporfin
  • Visual Acuity / physiology

Substances

  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin