Oral High Dose Dexamethasone for Pure Red Cell Aplasia Following ABO-Mismatched Allogeneic Peripheral Blood Stem Cell Transplantation: A Case Report

Indian J Hematol Blood Transfus. 2015 Jun;31(2):317-8. doi: 10.1007/s12288-013-0276-x. Epub 2013 Jun 9.

Abstract

Management of pure red cell aplasia following major ABO-mismatched hematopoietic stem cell transplantation is a therapeutic challenge. Various therapeutic modalities have been tried with variable responses, and patient remains transfusion dependent for a long time. We report here the use of pulsed oral high dose dexamethasone for pure red cell aplasia following ABO-mismatched allogeneic transplant with complete recovery.

Keywords: ABO-mismatched allogeneic stem cell transplantation; Oral pulsed high dose dexamethasone; Pure red cell aplasia.