MSA-PAD: DNA multiple sequence alignment framework based on PFAM accessed domain information

Bioinformatics. 2015 Aug 1;31(15):2571-3. doi: 10.1093/bioinformatics/btv141. Epub 2015 Mar 26.

Abstract

Here we present the MSA-PAD application, a DNA multiple sequence alignment framework that uses PFAM protein domain information to align DNA sequences encoding either single or multiple protein domains. MSA-PAD has two alignment options: gene and genome mode.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / genetics*
  • Databases, Factual*
  • Genome, Human
  • Humans
  • Protein Structure, Tertiary
  • Proteins / chemistry*
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA / methods*
  • Software*

Substances

  • Proteins
  • DNA