Clinical Evaluation of Coronary In-Stent Restenosis Using Dual-Source Computed Tomography

Echocardiography. 2015 Nov;32(11):1681-7. doi: 10.1111/echo.12932. Epub 2015 Mar 25.

Abstract

Objective: To explore the feasibility of dual-source computed tomography (DSCT) in the evaluation of coronary in-stent restenosis (ISR) by comparing the results of DSCT and selective coronary angiography (CAG).

Methods: In-stent restenosis examination results from DSCT were compared with those obtained using CAG.

Results: Among 173 stents studied, 156 yielded good quality images when evaluated with DSCT. CAG identified 38 ISR cases, while DSCT found 40. Among the 112 stents in the study with an inner diameter ≥3.0 mm, CAG identified 29 as having ISR, while DSCT reported the same finding in 30; among the 44 stents with inner diameter <3.0 mm, CAG identified ISR in 9, while DSCT found ISR in 10.

Conclusions: Stent inner diameter is a key factor influencing the imaging of the stent lumen. DSCT demonstrated a higher negative predictive value in ISR assessment, suggesting that it could replace CAG for assessing the patency of stents with a larger inner diameter (≥3 mm).

Keywords: coronary angiography; dual-source CT; in-stent restenosis.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Coronary Angiography*
  • Coronary Restenosis / diagnostic imaging*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Stents*
  • Tomography, X-Ray Computed*