Bilateral Warthin tumor in psoriatic patients in therapy with multiple immunosuppressive therapy

Int J Immunopathol Pharmacol. 2015 Mar;28(1):138-41. doi: 10.1177/0394632015572742.

Abstract

Anti-TNFα drugs have strongly changed the way in which we deal with moderate and severe psoriasis. However, it is debatable whether biological drugs could increase the risk of developing cancer. The correlation between anti-TNFα drugs and lymphomas is well-known and is reported in all the technical details of biologic drugs. However, the association between anti-TNFα agents and solid tumors is still controversial. The authors report a case of bilateral salivary gland tumor in a psoriatic patient treated with several immunosuppressive therapies including anti-TNFα inhibitors.

Keywords: TNFα therapy; Warthin tumor; psoriasis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antibodies, Monoclonal / adverse effects
  • Antibodies, Monoclonal / therapeutic use
  • Antirheumatic Agents / adverse effects
  • Antirheumatic Agents / therapeutic use
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Middle Aged
  • Psoriasis / drug therapy*
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors
  • Wilms Tumor / chemically induced*

Substances

  • Antibodies, Monoclonal
  • Antirheumatic Agents
  • Immunosuppressive Agents
  • Tumor Necrosis Factor-alpha