Tailoring medium energy proton beam to induce low energy nuclear reactions in ⁸⁶SrCl₂ for production of PET radioisotope ⁸⁶Y

Dmitri G Medvedev; Leonard F Mausner; Philip Pile

doi:10.1016/j.apradiso.2015.02.021

Tailoring medium energy proton beam to induce low energy nuclear reactions in ⁸⁶SrCl₂ for production of PET radioisotope ⁸⁶Y

Appl Radiat Isot. 2015 Jul:101:20-26. doi: 10.1016/j.apradiso.2015.02.021. Epub 2015 Mar 4.

Authors

Dmitri G Medvedev¹, Leonard F Mausner², Philip Pile²

Affiliations

¹ Collider-Accelerator Department, Brookhaven National Laboratory, Upton, NY 11973, USA. Electronic address: dmedvede@bnl.gov.
² Collider-Accelerator Department, Brookhaven National Laboratory, Upton, NY 11973, USA.

PMID: 25813003
DOI: 10.1016/j.apradiso.2015.02.021

Abstract

This paper reports results of experiments at Brookhaven Linac Isotope Producer (BLIP) aiming to investigate effective production of positron emitting radioisotope (86)Y by the low energy (86)Sr(p,n) reaction. BLIP is a facility at Brookhaven National Laboratory designed for the proton irradiation of the targets for isotope production at high and intermediate proton energies. The proton beam is delivered by the Linear Accelerator (LINAC) whose incident energy is tunable from 200 to 66 MeV in approximately 21 MeV increments. The array was designed to ensure energy degradation from 66 MeV down to less than 20 MeV. Aluminum slabs were used to degrade the proton energy down to the required range. The production yield of (86)Y (1.2+/-0.1 mCi (44.4+/-3.7) MBq/μAh) and ratio of radioisotopic impurities was determined by assaying an aliquot of the irradiated (86)SrCl2 solution by gamma spectroscopy. The analysis of energy dependence of the (86)Y production yield and the ratios of radioisotopic impurities has been used to adjust degrader thickness. Experimental data showed substantial discrepancies in actual energy propagation compared to energy loss calculations.

Keywords: BLIP; Energy degradation; Low energy reaction; Production; Yttrium-86.