Abstract
Excess caloric intake leads to both the growth of existing fat cells and the generation of new adipocytes. New findings show that PI3K-Akt2 signalling is involved in the differentiation of adult adipose precursor cells—a pathway not required for adipogenesis in the embryo.
MeSH terms
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Adipocytes, White / cytology*
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Adipogenesis / physiology*
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Animals
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Male
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Obesity / metabolism*
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Phosphatidylinositol 3-Kinases / metabolism*
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Proto-Oncogene Proteins c-akt / metabolism*
Substances
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Phosphatidylinositol 3-Kinases
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Akt2 protein, mouse
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Proto-Oncogene Proteins c-akt