First Probable Case of Subcutaneous Infection Due to Truncatella angustata: a New Fungal Pathogen of Humans?

J Clin Microbiol. 2015 Jun;53(6):1961-4. doi: 10.1128/JCM.00400-15. Epub 2015 Mar 25.

Abstract

Truncatella angustata is a coelomycetous fungus, typically associated with vascular plants as either an endophyte or a pathogen. This organism has not previously been implicated in human disease. This report describes a case of T. angustata subcutaneous infection in an immunocompetent patient. A conclusive diagnosis was achieved through partial sequencing of ribosomal DNA (rDNA) cluster. The patient was successfully treated with voriconazole followed by itraconazole.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Communicable Diseases, Emerging
  • Dermatomycoses*
  • Female
  • Humans
  • Leg / microbiology
  • Leg / pathology
  • Middle Aged
  • Molecular Sequence Data
  • Poland
  • Skin / microbiology
  • Skin / pathology
  • Xylariales*

Substances

  • Antifungal Agents

Associated data

  • GENBANK/KC241879
  • GENBANK/KC241880