Updates in vaccination: recommendations for adult inflammatory bowel disease patients

World J Gastroenterol. 2015 Mar 21;21(11):3184-96. doi: 10.3748/wjg.v21.i11.3184.

Abstract

Treatment regimens for inflammatory bowel disease (IBD) incorporate the use of a variety of immunosuppressive agents that increase the risk of infections. Prevention of many of these infections can be achieved by the timely and judicious use of vaccinations. IBD patients tend to be under-immunized. Some of the contributing factors are lack of awareness regarding the significance of vaccinating IBD patients, misperception about safety of vaccinations in immunocompromised patients, ambiguity about the perceived role of the gastroenterologist in contrast to the primary care physician and unavailability of vaccination guidelines focused on IBD population. In general, immunocompetent IBD patients can be vaccinated using standard vaccination recommendations. However there are special considerations for IBD patients receiving immunosuppressive therapy, IBD travelers and pregnant women with IBD. This review discusses current vaccination recommendations with updates for adult IBD patients. Centers for Disease Control and Prevention 2013 vaccination guidelines with 2014 updates and the Advisory Committee on Immunization Practices recommendations have been highlighted as a primary source of recommendations.

Keywords: Centers for Disease Control and Prevention; Immunocompromised; Influenza; Inflammatory bowel disease; Pneumococcal; Vaccination.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Immunization / adverse effects
  • Immunization / methods*
  • Immunization / standards
  • Immunization Schedule
  • Immunocompromised Host*
  • Immunosuppressive Agents / adverse effects*
  • Inflammatory Bowel Diseases / diagnosis
  • Inflammatory Bowel Diseases / drug therapy*
  • Inflammatory Bowel Diseases / immunology
  • Male
  • Middle Aged
  • Opportunistic Infections / diagnosis
  • Opportunistic Infections / immunology
  • Opportunistic Infections / prevention & control*
  • Opportunistic Infections / transmission
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Complications, Infectious / immunology
  • Pregnancy Complications, Infectious / prevention & control
  • Risk Factors
  • Travel
  • Treatment Outcome

Substances

  • Immunosuppressive Agents