Guidelines for cytogenetic investigations in tumours

Rosalind J Hastings; Nick Bown; Maria G Tibiletti; Maria Debiec-Rychter; Roberta Vanni; Blanca Espinet; Nadine van Roy; Paul Roberts; Eva van den Berg-de-Ruiter; Alain Bernheim; Jacqueline Schoumans; Steve Chatters; Zuzana Zemanova; Marian Stevens-Kroef; Annet Simons; Sverre Heim; Marta Salido; Bauke Ylstra; David R Betts; Tumour Best Practice meeting; Eurogentest

doi:10.1038/ejhg.2015.35

Guidelines for cytogenetic investigations in tumours

Eur J Hum Genet. 2016 Jan;24(1):6-13. doi: 10.1038/ejhg.2015.35. Epub 2015 Mar 25.

Authors

Rosalind J Hastings¹, Nick Bown², Maria G Tibiletti³, Maria Debiec-Rychter⁴, Roberta Vanni⁵, Blanca Espinet⁶, Nadine van Roy⁷, Paul Roberts⁸, Eva van den Berg-de-Ruiter⁹, Alain Bernheim¹⁰, Jacqueline Schoumans¹¹, Steve Chatters¹², Zuzana Zemanova¹³, Marian Stevens-Kroef¹⁴, Annet Simons¹⁴, Sverre Heim¹⁵, Marta Salido⁶, Bauke Ylstra¹⁶, David R Betts¹⁷; Tumour Best Practice meeting; Eurogentest

Affiliations

¹ Women's Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
² Northern Genetics Service, Institute of Genomic Medicine, Central Parkway, Newcastle, UK.
³ UO Anatomia Patologica, Ospedale di Circolo-Polo Universitario, Varese, Italy.
⁴ Laboratory for Genetics of Malignant Disorders, Department of Human Genetics, University Hospital Gasthuisberg, UZ Leuven, Leuven, Belgium.
⁵ Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
⁶ Laboratori de Citogenètica Molecular, Servei de Patologia, Hospital del Mar, Barcelona, Spain.
⁷ Centre for Medical Genetics, University Hospital Ghent, Ghent, Belgium.
⁸ Cytogenetics Department, St James's Hospital, Leeds, UK.
⁹ Department of Genetics, University of Groningen, University Medical Centre Groningen, RB Groningen, The Netherlands.
¹⁰ Génétique des tumeurs (INSERM U985), Laboratoire de Cytogénétique, Pathologie Moléculaire Gustave Roussy, Paris-Villejuif, France.
¹¹ Cancer Cytogenetic Unit, Lausanne University Hospital, CHUV, Lausanne, Switzerland.
¹² Haematology, Cellular and Molecular Diagnostic Service, Great Ormond St Hospital, London, UK.
¹³ Center of Oncocytogenetics, Institute of Clinical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
¹⁴ Radboud University Nijmegen Medical Centre Department of Human Genetics, HB Nijmegen, The Netherlands.
¹⁵ Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
¹⁶ Department of Pathology, Cancer Center Amsterdam, VU University Medical Center, MB Amsterdam, The Netherlands.
¹⁷ Department of Clinical Genetics, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.

No abstract available

Publication types

Guideline
Research Support, Non-U.S. Gov't

MeSH terms

Accreditation / legislation & jurisprudence
Biomarkers / metabolism
Biopsy, Fine-Needle / standards
Cytogenetic Analysis / methods
Cytogenetic Analysis / standards*
Europe
Gene Expression
High-Throughput Nucleotide Sequencing / standards*
Humans
In Situ Hybridization, Fluorescence / standards
Neoplasm Proteins / genetics*
Neoplasms / diagnosis*
Neoplasms / genetics*
Neoplasms / pathology
Paraffin Embedding / methods
Paraffin Embedding / standards
Research Design / standards
Sensitivity and Specificity
Tissue Array Analysis / standards
Tissue Fixation / methods
Tissue Fixation / standards

Substances

Biomarkers
Neoplasm Proteins