Solid-binding peptides: smart tools for nanobiotechnology

Trends Biotechnol. 2015 May;33(5):259-68. doi: 10.1016/j.tibtech.2015.02.005. Epub 2015 Mar 19.

Abstract

Over the past decade, solid-binding peptides (SBPs) have been used increasingly as molecular building blocks in nanobiotechnology. These peptides show selectivity and bind with high affinity to the surfaces of a diverse range of solid materials including metals, metal oxides, metal compounds, magnetic materials, semiconductors, carbon materials, polymers, and minerals. They can direct the assembly and functionalisation of materials, and have the ability to mediate the synthesis and construction of nanoparticles and complex nanostructures. As the availability of newly synthesised nanomaterials expands rapidly, so too do the potential applications for SBPs.

Keywords: bioconjugation; biomaterials; functionalisation; nanomaterials; solid-binding peptides.

Publication types

  • Review

MeSH terms

  • Amino Acid Motifs
  • Nanostructures / chemistry*
  • Nanotechnology / methods
  • Nanotechnology / trends*
  • Peptides / chemistry*
  • Protein Binding

Substances

  • Peptides