Abstract
A novel direct transformation of hydrazones to acyloxylated pyrazoles by copper-catalyzed regioselective olefinic C(sp(2))-H bond cycloamination and acyloxylation was performed under mild conditions, which combines the formation of the pyrazole skeleton and installation of an acyloxyl group in a single step, using facile carboxylic acids as the acyloxylation reagents.
MeSH terms
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Carboxylic Acids / chemistry
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Catalysis
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Copper / chemistry*
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Cyclization
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Drug Design
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Hydrazines / chemistry
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Hydrazones / chemistry*
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Hydrogen Bonding
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Ligands
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Metals / chemistry
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Models, Chemical
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Molecular Structure
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Organic Chemicals / chemistry
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Pyrazoles / chemistry*
Substances
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Carboxylic Acids
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Hydrazines
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Hydrazones
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Ligands
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Metals
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Organic Chemicals
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Pyrazoles
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hydrazine
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Copper