Abstract
Catalytic trifluoromethylation of aryl- and vinylboronic acids by 2-cyclopropyl-1-(trifluoromethyl)benzo[b]thiophenium triflate is described. In the presence of a catalytic amount of CuOAc and 2,4,6-collidine in ethyl acetate, the reaction proceeded in good to high yields for various substrates under mild reaction conditions at room temperature.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetates / chemistry*
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Boronic Acids / chemistry*
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Catalysis
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Copper / chemistry*
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Hydrocarbons, Fluorinated / chemistry*
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Mesylates / chemistry*
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Methylation
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Molecular Structure
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Pyridines / chemistry*
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Thiophenes / chemistry*
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Vinyl Compounds / chemistry*
Substances
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2-cyclopropyl-1-(trifluoromethyl)benzo(b)thiophenium triflate
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Acetates
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Boronic Acids
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Hydrocarbons, Fluorinated
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Mesylates
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Pyridines
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Thiophenes
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Vinyl Compounds
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ethyl acetate
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Copper
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gamma-collidine
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trifluoromethanesulfonic acid