Comparative study on the antioxidant activities of extracts of Coreopsis tinctoria flowering tops from Kunlun Mountains, Xinjiang, north-western China

Nat Prod Res. 2016;30(4):429-32. doi: 10.1080/14786419.2015.1015019. Epub 2015 Mar 17.

Abstract

Coreopsis tinctoria flowering tops (CTFs) from the Kunlun Mountains in Xinjing (north-western China) have been used for tea production for about a century. This study aims to assess the antioxidant activities and total phenolic, flavonoid and proanthocyanidin contents of various solvent extracts of CTF. CTF was extracted using n-hexane, chloroform, ethyl acetate, n-butanol, 75% aqueous ethanol (AEE) and water. The antioxidant activities of the CTF extracts were investigated through DPPH, ABTS, *OH, *O2(-), total antioxidant capacity and reducing power assays. The results showed that n-butanol extract showed the highest contents of total phenols and flavonoids, with DPPH, ABTS and *OH radical-scavenging activities with IC50 values of 134, 90.72 and 13.8 μg mL(-1), respectively. The AEE demonstrated the strongest DPPH and ABTS radical-scavenging activities, with IC50 values of 103 and 75.16 μg mL(-1), respectively. Given its high antioxidant effect, CTF is a good source of natural antioxidants or functional food materials.

Keywords: Coreopsis tinctoria Nutt; antioxidant activity; radical scavenging activity.

Publication types

  • Comparative Study

MeSH terms

  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Biphenyl Compounds / chemistry
  • China
  • Coreopsis / chemistry*
  • Flavonoids / analysis
  • Flowering Tops / chemistry
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / pharmacology
  • Hydroxyl Radical
  • Phenols / analysis
  • Picrates / chemistry
  • Plant Extracts / pharmacology*
  • Proanthocyanidins / analysis
  • Solvents

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Flavonoids
  • Free Radical Scavengers
  • Phenols
  • Picrates
  • Plant Extracts
  • Proanthocyanidins
  • Solvents
  • proanthocyanidin
  • Hydroxyl Radical
  • 1,1-diphenyl-2-picrylhydrazyl