Metastasectomy for stage IV melanoma

Surg Oncol Clin N Am. 2015 Apr;24(2):279-98. doi: 10.1016/j.soc.2014.12.006. Epub 2015 Jan 27.

Abstract

Metastatic melanoma has an unpredictable natural history but a predictably high mortality. Despite recent advances in systemic therapy, many patients do not respond, or develop resistance to drug therapy. Surgery has consistently shown good outcomes in appropriately selected patients. It is likely to be even more successful in the era of more effective medical treatment. Surgery should remain a strongly considered option for metastatic melanoma.

Keywords: Metastasectomy; Metastatic melanoma; Oligometastases; Stage IV melanoma; Surgery.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Melanoma / pathology*
  • Melanoma / surgery*
  • Melanoma / therapy
  • Metastasectomy*
  • Neoplasm Staging
  • Prognosis
  • Randomized Controlled Trials as Topic
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery*
  • Skin Neoplasms / therapy
  • Survival Analysis