A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo

Cell Death Dis. 2015 Mar 12;6(3):e1679. doi: 10.1038/cddis.2015.54.

Authors

E F Lee¹, M Takiguchi², A Pettikiriarachchi², M Evangelista², D C S Huang¹, R A Dickins¹, W D Fairlie¹

Affiliations

¹ 1] Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
² Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blood Platelets / metabolism
Female
Male
Mice
Mice, Transgenic
Models, Animal
Peptide Fragments / pharmacology*
Proto-Oncogene Proteins / pharmacology*
Proto-Oncogene Proteins c-bcl-2 / genetics
Proto-Oncogene Proteins c-bcl-2 / metabolism*

Substances

Bax protein (53-86)
Peptide Fragments
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2