Intestinal carriage of Shewanella xiamenensis simulating carriage of OXA-48-producing Enterobacteriaceae

Alberto Antonelli; Domenica Maria Di Palo; Angelo Galano; Sabrina Becciani; Carlotta Montagnani; Patrizia Pecile; Luisa Galli; Gian Maria Rossolini

doi:10.1016/j.diagmicrobio.2015.02.008

Intestinal carriage of Shewanella xiamenensis simulating carriage of OXA-48-producing Enterobacteriaceae

Diagn Microbiol Infect Dis. 2015 May;82(1):1-3. doi: 10.1016/j.diagmicrobio.2015.02.008. Epub 2015 Feb 21.

Authors

Alberto Antonelli¹, Domenica Maria Di Palo², Angelo Galano², Sabrina Becciani³, Carlotta Montagnani³, Patrizia Pecile⁴, Luisa Galli⁵, Gian Maria Rossolini⁶

Affiliations

¹ Department of Medical Biotechnologies, University of Siena, Policlinico Santa Maria alle Scotte, Viale Bracci, I-53100 Siena, Italy; Department of Experimental and Clinical Medicine, University of Florence, Piastra dei Servizi, Via San Damiano, I-50134 Florence, Italy.
² Department of Medical Biotechnologies, University of Siena, Policlinico Santa Maria alle Scotte, Viale Bracci, I-53100 Siena, Italy; Clinical Microbiology and Virology Unit, Careggi University Hospital, Piastra dei Servizi, Via San Damiano, I-50134 Florence, Italy.
³ Department of Health Sciences, University of Florence, Viale Pieraccini, I-50139 Florence, Italy.
⁴ Clinical Microbiology and Virology Unit, Careggi University Hospital, Piastra dei Servizi, Via San Damiano, I-50134 Florence, Italy.
⁵ Department of Health Sciences, University of Florence, Viale Pieraccini, I-50139 Florence, Italy; Meyer Children's University Hospital, Viale Pieraccini, I-50139 Florence, Italy.
⁶ Department of Medical Biotechnologies, University of Siena, Policlinico Santa Maria alle Scotte, Viale Bracci, I-53100 Siena, Italy; Department of Experimental and Clinical Medicine, University of Florence, Piastra dei Servizi, Via San Damiano, I-50134 Florence, Italy; Clinical Microbiology and Virology Unit, Careggi University Hospital, Piastra dei Servizi, Via San Damiano, I-50134 Florence, Italy. Electronic address: gianmaria.rossolini@unifi.it.

PMID: 25766005
DOI: 10.1016/j.diagmicrobio.2015.02.008

Abstract

Positivity for bla(OXA-48)-like carbapenemase genes was revealed by molecular testing of a surveillance rectal swab from a patient who had previously been colonized and infected by an OXA-48-producing Klebsiella pneumoniae. Positivity was due to a coincidental carriage of Shewanella xiamenensis harboring a new bla(OXA-48)-like gene, while the K. pneumoniae was no longer present.

Keywords: Carbapenemase-producing Enterobacteriaceae; Molecular testing; OXA-48 carbapenemase; Shewanella xiamenensis; Surveillance.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Carrier State / epidemiology*
Carrier State / microbiology*
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
Gram-Negative Bacterial Infections / epidemiology*
Gram-Negative Bacterial Infections / microbiology*
Humans
Infant
Klebsiella pneumoniae / enzymology
Klebsiella pneumoniae / genetics
Klebsiella pneumoniae / isolation & purification
Molecular Sequence Data
Rectum / microbiology
Sequence Analysis, DNA
Shewanella / enzymology*
Shewanella / genetics
Shewanella / isolation & purification*
beta-Lactamases / genetics*
beta-Lactamases / metabolism

Substances

DNA, Bacterial
beta-Lactamases
oxacillinase

Associated data

GENBANK/KP264118
GENBANK/KP264119