Malignant syphilis in a HIV infected patient

Sex Transm Dis. 2015 Apr;42(4):223-5. doi: 10.1097/01.olq.0000462908.84464.52.

Abstract

We present a 47 year old female white HIV-1 infected patient with multiple painless rupioid skin lesions, a CD4 count of 155 cells/mm3, positive syphilis serology and a histopathology conspicuous for malignant syphilis. She could be successfully treated with Benzathine-Benzylpenicillin (Retarpen®) 2,4 Mega I.E., 3x intramuscularly in weekly intervals.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Blotting, Western
  • CD4 Lymphocyte Count
  • Drug Administration Schedule
  • Female
  • HIV Infections / complications
  • HIV Infections / immunology*
  • HIV-1 / immunology*
  • Humans
  • Middle Aged
  • Penicillin G Benzathine / administration & dosage*
  • Syphilis, Cutaneous / drug therapy*
  • Syphilis, Cutaneous / etiology
  • Syphilis, Cutaneous / immunology
  • Treatment Outcome
  • Viral Load

Substances

  • Anti-Bacterial Agents
  • Penicillin G Benzathine