Prevalence of resistance to aminoglycosides and fluoroquinolones among Pseudomonas aeruginosa strains in a University Hospital in Northeastern Poland

Anna Diana Michalska; Pawel Tomasz Sacha; Dominika Ojdana; Anna Wieczorek; Elzbieta Tryniszewska

doi:10.1590/s1517-83822014000400041

Prevalence of resistance to aminoglycosides and fluoroquinolones among Pseudomonas aeruginosa strains in a University Hospital in Northeastern Poland

Braz J Microbiol. 2015 Mar 4;45(4):1455-8. doi: 10.1590/s1517-83822014000400041. eCollection 2014.

Authors

Anna Diana Michalska¹, Pawel Tomasz Sacha¹, Dominika Ojdana¹, Anna Wieczorek¹, Elzbieta Tryniszewska¹

Affiliation

¹ Department of Microbiological Diagnostics and Infectious Immunology Medical University of Bialystok Poland Department of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Poland.

Abstract

The present study was conducted to investigate the prevalence of genes encoding resistance to aminoglycosides and fluoroquinolones among twenty-five Pseudomonas aeruginosa isolated between 2002 and 2009. In PCR, following genes were detected: ant(2″)-Ia in 9 (36.0%), aac(6')-Ib in 7 (28.0%), qnrB in 5 (20.0%), aph(3″)-Ib in 2 (8.0%) of isolates.

Keywords: Pseudomonas aeruginosa; aminoglycoside-modifying enzymes; plasmid-mediated resistance to aminoglycosides and fluoroquinolones.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aminoglycosides / pharmacology*
Anti-Bacterial Agents / pharmacology*
Drug Resistance, Bacterial*
Fluoroquinolones / pharmacology*
Genes, Bacterial
Genotype
Hospitals, University
Humans
Microbial Sensitivity Tests
Poland / epidemiology
Polymerase Chain Reaction
Prevalence
Pseudomonas Infections / epidemiology
Pseudomonas Infections / microbiology*
Pseudomonas aeruginosa / drug effects*
Pseudomonas aeruginosa / genetics
Pseudomonas aeruginosa / isolation & purification

Substances

Aminoglycosides
Anti-Bacterial Agents
Fluoroquinolones